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LUNG CANCER GROUP

Members

Irene Najjingo BBLT, Msc. CEB (Group Lead)

Dr Baluku Joseph MBChB, M.Med, M. Sc

Dr Grace Soka, MB ChB, Msc. Public health

Irene Najjingo BBLT, Msc. Epidemiology

Dr. Margaret Mbabazi MB ChB, M.Med Radiology

Dr. Treasure Ibingira MB ChB, M.Med Surgery

Dr. Gift Bunyatta MBChB, M.Med Pathology

 

Vision

To become a centre of excellence in lung cancer care in East Africa.

Mission

To empower communities in East Africa to combat lung cancer through collaborative research, early detection, improved treatment and access to care as well improve the quality of life for those affected by the disease.

Research

  1. LCH Project –Ongoing

Epidemiology, molecular characterization and imaging of Lung cancer and the relationship to HIV-1 infection in Uganda and Tanzania is a five year study that received funding from the NIH

To understand the clinical and genetic risk factors for lung cancer and assess how lung cancer is related to HIV.

Progress: We are currently enrolling and following up lung cancer patients to assess for outcomes

  1. MTB infection and DNA damage in HIV-associated lung cancer in Uganda – Completed

Aim: To compare cytogenetic abnormalities among people living with HIV (PLWH) with and without previous exposure to Mycobacterium tuberculosis (Mtb) (both latent tuberculosis infection and active tuberculosis)

https://www.sciencedirect.com/science/article/abs/pii/S138357182300058X

 

  1. HIV-related lung cancer in Uganda: a cohort study

Aim: Describe a cohort of People with HIV (PWH) and lung cancer at the Uganda Cancer Institute.

https://infectagentscancer.biomedcentral.com/articles/10.1186/s13027-022-00439-x

 

  1. RADIOLOGY-PATHOLOGICAL CORRELATION, VALIDATION OF LUNG RADS AND DEVELOPMENT OF A LUNG CANCER SCREENING PROTOCOL IN UGANDA – COMPLETED

Aim was to determine the histopathological  subtypes of lung cancer in Uganda and  describe their corresponding appearance on chest Computed Tomography.

Conclusion: The most common lung cancer subtypes in Uganda are adenocarcinoma and squamous cell carcinoma.  Both subtypes tend to be large centrally located masses, ovoid and had lobulated margins radiologically

  1. Integrating Lung cancer screening services into HIV care, Generating evidence/baseline data for the implementation of Lung Cancer Screening in HIV care – In progress

Aims: To Implement Lung Cancer screening among PLWH using LDCT in the selected Care and Treatment Centers.