MLI Report 2024 JuneDownload
COVID-19 vaccines cannot prevent infection, though they are thought to prevent severe disease. Failure to prevent infection has made COVID-19 persist in vaccinatedindividuals, all in the face of low vaccination rates in sub-Saharan Africa. The need for vaccines that can …
Abstract This epidemic presented unique challenges that the Uganda government had not faced before. Mubende district — the epicenter of the epidemic — is traversed by a major highway that connects Uganda to the neighboring countries of Democratic Republic of …
Abstract Background: During the COVID-19 pandemic, TB mortality increased while diagnoses decreased, likely due to care disruption. In March, 2020, Uganda—a country with high TB burden, implemented a COVID-19 lockdown with associated decrease in TB diagnoses. This study aims to …
Abstract Prior research suggests that fluvoxamine, a selective serotonin reuptake inhibitor (SSRI) used for the treatment of obsessive-compulsive disorder and major depressive disorder, could be repurposed against COVID-19. We undertook a prospective interventional open-label cohort study to evaluate the efficacy and tolerability of fluvoxamine among inpatients with laboratory-confirmed COVID-19 in Uganda. The main outcome was all-cause mortality. Secondary outcomes were hospital discharge and complete symptom …
Abstract Introduction Evidence that supports the use of COVID-19 convalescent plasma (CCP) for treatment of COVID-19 is increasingly emerging. However, very few African countries have undertaken the collection and processing of CCP. The aim of this study was to assess …
Abstract Introduction Despite the limited evidence for its effectiveness, thermal screening at points of entry has increasingly become a standard protocol in numerous parts of the globe in response to the COVID-19 pandemic. We sought to determine the effectiveness of …