Inside this issue • Preliminary study results from the COVIDEPI study • Updates from the Coronavirus Immune Therapy (COVIDIT) Study launch • How to breathe during a pandemic: implications of COVID-19 for people with chronic lung disease Click here to …
This project is part of the EDCTP2 programme supported by the European Union
EDCTP TMA Grant Award
Award number: TMA2020CDF-3194
Grant Amount: 150,000 Euros
Title: Microbiome fuels Th17 mediated airway inflammation in COPD among HIV-infected individuals
Principal investigator: Alex Kayongo, MBChB, MSc, PhD fellow, MakCHS
Makerere University Lung Institute unveils first-of-its-kind Pulmonary Function Assessment equipment
Abstract The Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published the complete 2023 GOLD report, which can be freely downloaded from its webpage (www.goldcopd.org) together with a “pocket guide” and “teaching slide set” [1]. It contains important changes …
Abstract Prior research suggests that fluvoxamine, a selective serotonin reuptake inhibitor (SSRI) used for the treatment of obsessive-compulsive disorder and major depressive disorder, could be repurposed against COVID-19. We undertook a prospective interventional open-label cohort study to evaluate the efficacy and tolerability of fluvoxamine among inpatients with laboratory-confirmed COVID-19 in Uganda. The main outcome was all-cause mortality. Secondary outcomes were hospital discharge and complete symptom …
Abstract Albert Einstein taught us that “everything is relative.” People’s experience of physical activity (PA) is no different, with “relativism” particularly pertinent to the perception of intensity. Markers of absolute and relative intensities of PA have different but complimentary utilities, …
Abstract Sub-Saharan Africa has increased morbidity and mortality related to chronic obstructive pulmonary disease (COPD). COPD among people living with HIV (PLWH) has not been well studied in this region, where HIV/AIDS is endemic. Increasing evidence suggests that respiratory microbial …
Abstract Chronic Obstructive Pulmonary Disease (COPD) has significantly contributed to global mortality, with three million deaths reported annually. This impact is expected to increase over the next 40 years, with approximately 5 million people predicted to succumb to COPD-related deaths …
Abstract Background The STREAM stage 2 trial assessed two bedaquiline-containing regimens for rifampicin-resistant tuberculosis: a 9-month all-oral regimen and a 6-month regimen containing an injectable drug for the first 2 months. We did a within-trial economic evaluation of these regimens. …
Abstract One of the major consequences of Africa’s rapid urbanisation is the worsening air pollution, especially in urban centres. However, existing societal challenges such as recovery from the COVID-19 pandemic, poverty, intensifying effects of climate change are making prioritisation of …